Download E-books High-Yield™ Cell and Molecular Biology (High-Yield Series) PDF

High-Yield™ mobilephone and Molecular Biology, 3rd Edition offers the basic details wanted for USMLE Step 1 evaluate and path learn. It covers present phone and molecular biology suggestions and rules with a medical focus—what a doctor must recognize to appreciate, diagnose, and deal with human disorder. Molecular biology is frequently taught inside of numerous classes resembling biochemistry, microbiology, and histology; therefore, a consolidated evaluate e-book in molecular biology is principally worthwhile in getting ready for the USMLE Step 1.

This variation has been streamlined to take away content material lined in different High-Yield™ books comparable to histopathology and microbiology. pictures were positioned in the direction of the fitting textual content. New figures comprise DNA melting curve and circulation cytometry.

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A hundred and fifteen Site-Directed Mutagenesis and Knockout Animals . . . . . . . . . . . . . . . . . . . . . . . . . 117 Northern Blot (mRNA) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 Western Blot (Protein) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 121 Human Immunodeficiency Virus (HIV) constitution . . . . . . . . . . . . . . . . . . . . . . . . . 123 Ligase Chain response (LCR) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . one hundred twenty five move Cytometry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127 15 identity of Human affliction Genes I. II. III. IV. V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89 Clonal choice idea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89 The B Lymphocyte (B telephone) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89 The T Lymphocyte (T telephone) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ninety three medical issues . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ninety five problems of Phagocytic functionality . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ninety six Systemic Autoimmune issues . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ninety seven Organ-Specific Autoimmune problems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ninety seven 14 Molecular Biology innovations I. II. III. IV. V. VI. VII. VIII. IX. X. XI. XII. XIII. XIV. xi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 common good points . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 id of a Human disorder Gene via a Chromosome Abnormality . . . . . 129 id of a Human illness Gene via natural Transcript Mapping . . . . . . a hundred thirty identity of a Human illness Gene via huge Scale DNA Sequencing . . . . . 131 id of a Human affliction Gene via comparability of Human and Mouse Maps . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132 LWBK771-FM_pi-xvi. qxd 9/30/10 1:33 PM web page xii Aptara Inc sixteen Gene remedy I. II. III. IV. V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133 Gene treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133 Ex Vivo and In Vivo Gene remedy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134 Integration into Host mobilephone Chromosomes or as Episomes . . . . . . . . . . . . . . . . . . . 134 Viral Vectors utilized in Gene remedy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134 Nonviral Vectors utilized in Gene remedy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . a hundred thirty five Appendix 1: The Genetic Code . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137 Appendix 2: Amino Acids . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138 Appendix three: Chromosomal destinations of Human Genetic illnesses . . . . . . . . . . . . . . . . . 139 determine credit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . one hundred forty five Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147 LWBK771-FM_pi-xvi. qxd 9/30/10 1:33 PM web page xiii Aptara Inc Abbreviations xiii LWBK771-FM_pi-xvi. qxd 9/30/10 1:33 PM web page xiv Aptara Inc xiv ABBREVIATIONS LWBK771-FM_pi-xvi. qxd 9/30/10 1:33 PM web page xv Aptara Inc ABBREVIATIONS xv LWBK771-FM_pi-xvi. qxd 9/30/10 1:33 PM web page xvi Aptara Inc xvi ABBREVIATIONS LWBK771-c01_p1-8. qxd 9/29/10 6:48PM web page 1 aptara bankruptcy 1 Chromosomal DNA I The Biochemistry of Nucleic Acids (Figure 1-1). A nucleoside contains a nitrogenous base and a sugar.

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